Tesofensine is an innovative compound originally developed to treat neurological disorders, whose effects have revealed a powerful potential in appetite reduction and rapid weight loss. By acting on the regulation of neurotransmitters — dopamine, noradrenaline, and serotonin — it promotes prolonged satiety, increases mental energy, and stimulates metabolism.
Tesofensine acts as a triple reuptake inhibitor (TRI) of dopamine, noradrenaline, and serotonin. This unique mechanism increases the availability of all three neurotransmitters in the synapses, producing powerful and prolonged appetite suppression via the hypothalamic hunger regulation centers.
Unlike traditional appetite suppressants, Tesofensine reduces caloric intake without catabolic effects on muscle mass, while improving concentration and mood through its dopaminergic and serotonergic action.
| Class | Triple Reuptake Inhibitor (TRI) |
| Targets | Dopamine · Noradrenaline · Serotonin |
| Format | 30 ml bottle · 30 to 60 days of use |
| Usage | 0.5 to 1 ml each morning on an empty stomach |
| Research use | For laboratory research use only |
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