GLOW

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GLOW is a synergistic peptide complex formulated with GHK-Cu, BPC-157 and TB-500. Studied in scientific research for its effects on skin rejuvenation, collagen stimulation, tissue repair and musculoskeletal recovery. For research use only.

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SLU-PP-332 is a synthetic compound developed at Saint Louis University, a pan-ERR agonist of nuclear receptors ERRα, ERRβ, and ERRγ (estrogen-related receptors). It is classified as an exercise mimetic — a molecule that pharmacologically reproduces the cellular adaptations of aerobic physical activity.

OVERVIEW

The central molecular mechanism of SLU-PP-332 relies on ERRα activation, which controls gene networks governing oxidative metabolism, mitochondrial biogenesis, and energy homeostasis. These pathways are naturally activated by endurance exercise — SLU-PP-332 reproduces them without physical exertion.

Notably, SLU-PP-332 induces DDIT4 expression specifically via ERRα, recapitulating a key genetic response observed after short bouts of human aerobic exercise. Its doping potential has been identified by WADA (World Anti-Doping Agency).

RESEARCH AREAS
Muscle endurance — 20–30% improvement in running distance and time; increase of fast oxidative muscle fibers (type IIa) in treated mice.
Fat metabolism — increased fatty acid oxidation and energy expenditure; reduced fat mass accumulation without changes in food intake.
Metabolic syndrome — reduction of diet-induced obesity, improved glucose tolerance and insulin sensitivity (DIO and ob/ob murine models, 28 days).
Mitochondrial biogenesis — increased mitochondrial function and cellular respiration in skeletal muscle cell lines.
Cardioprotection — protection against pressure-overload cardiac hypertrophy (murine models) via activation of the cardiac fatty acid oxidation (FAO) program.

CHEMICAL DATA
Molecular weight ~382 Da
Targets ERRα (EC50 98 nM), ERRβ (230 nM), ERRγ (430 nM)
Other names Pan-ERR agonist, Exercise mimetic
Form Powder / Solution
Purity >99% HPLC

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